ellibsЭлектронные библиотекиRussian Digital Libraries Journal1562-5419Казанский (Приволжский) федеральный университетellibs-20Research ArticleСтатьиНизкоуровневая реализация модели норадреналиновой подсистемы нейронной импульсной сетиThe low level implementation of the noradrenaline pathways of spiking neural networkСафандееваЮ. С.julia.safandeeva@gmail.comТалановМ. О.max.talanov@gmail.comКазанский (Приволжский) федеральный университетRussian Federation201628062016193251286Copyright © Сафандеева Ю.С., Таланов М.О., 20162016Сафандеева Ю.С., Таланов М.О.Сафандеева Ю.С., Таланов М.О.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ellibs.elpub.ru/jour/article/view/20

На основе модели «Куба эмоций» Лёвхейма [1] и нейронных сетей предложено воспроизвести базовые эмоциональные состояния, описанные Сильвеном Томкинсом [2]. Рассмотрено влияние на параметры вычислительной системы нейромодулятора норадреналина с учетом его роли и функции в головном мозге. Описаны реализация низкоуровневой модели норадреналиновой подсистемы и её моделирование во фреймворке «Nest Initiative».

We propose to re-implement basic emotions described by Silvian Tomkins via "Cube of emotions" of Hugo Lövheim, and spiking NNs. We use the basic mechanism of noradrenaline neuromodulation and map it to the influence over computational processes in modern computers. We implement noradrenaline pathways via neuro-biological simulator NEST.

куб ЛёвхейманорадреналинNESTNeuCogARReferencesLövheim H. A new three-dimensional model for emotions and monoamine neurotransmitters // Med Hypotheses. 2012. V. 8. P. 341–348.Lövheim H. A new three-dimensional model for emotions and monoamine neurotransmitters // Med Hypotheses. 2012. V. 8. P. 341–348.Tomkins S. Affect theory // In: P. Ekman, W. Friesen, P. Ellsworth, Eds. Emotions in the Human Face. Cambridge: Cambridge University Press, 1982. P. 355–395.Tomkins S. Affect theory // In: P. Ekman, W. Friesen, P. Ellsworth, Eds. Emotions in the Human Face. Cambridge: Cambridge University Press, 1982. P. 355–395.Helena F., Debra K. Emotions and social movements // Routledge. 2015. P. 19–41.Helena F., Debra K. Emotions and social movements // Routledge. 2015. P. 19–41.Michael Cole M. Culture and cognitive science // Outlines. 2003. No 1. P. 4.Michael Cole M. Culture and cognitive science // Outlines. 2003. No 1. P. 4.Ёлкин С.C., Клышинский Э.С., Максимов В.Ю., Мусаева Т.Н. Модель бионической нейронной сети и ее применения // ИПМ им. М.В. Келдыша РАН. 2008. С. 7–9.Ёлкин С.C., Клышинский Э.С., Максимов В.Ю., Мусаева Т.Н. Модель бионической нейронной сети и ее применения // ИПМ им. М.В. Келдыша РАН. 2008. С. 7–9.Purves D., Augustine G.J., Fitzpatrick D. et al. Neuroscience: 2nd edition // (MA): Sinauer Associates. 2001. P. 4–8.Purves D., Augustine G.J., Fitzpatrick D. et al. Neuroscience: 2nd edition // (MA): Sinauer Associates. 2001. P. 4–8.Simon Haykin. Neural Networks A Comprehensive Foundation. Second Edition. MsMaster University. 2006. P. 23–28.Simon Haykin. Neural Networks A Comprehensive Foundation. Second Edition. MsMaster University. 2006. P. 23–28.Колесницкий О.К., Бокоцей И.В., Яремчук С.С. Аппаратная реализация элементов импульсных нейронных сетей с использованием биспин-приборов, Часть 1 // XII Всеросиийская научно-техническая конференция «Нейроинформатика», 2010. C. 122–127.Колесницкий О.К., Бокоцей И.В., Яремчук С.С. Аппаратная реализация элементов импульсных нейронных сетей с использованием биспин-приборов, Часть 1 // XII Всеросиийская научно-техническая конференция «Нейроинформатика», 2010. C. 122–127.Сланевская Н.М. Мозг, мышление и общество. Часть 1. Центр Междисциплинарной нейронауки, 2012. C. 26–35.Сланевская Н.М. Мозг, мышление и общество. Часть 1. Центр Междисциплинарной нейронауки, 2012. C. 26–35.Lodish H., Berk A., Zipursky SL. et al. Molecular Cell Biology, 4th edition. New York: W.H. Freeman, 2000. P. 287–298.Lodish H., Berk A., Zipursky SL. et al. Molecular Cell Biology, 4th edition. New York: W.H. Freeman, 2000. P. 287–298.Richard Finkel, Michelle Alexia Clark, Luigi X. Cubeddu. Pharmacology. Lippincott Williams & Wilkins, 2008. P. 35–43.Richard Finkel, Michelle Alexia Clark, Luigi X. Cubeddu. Pharmacology. Lippincott Williams & Wilkins, 2008. P. 35–43.Päivi Marjamäki. Imaging of dopamine and serotonin transporters Pre-Clinical Studies with Radiotracers for Positron Emission Tomography // Turun Yliopisto University of Turku, 2011. P. 14–15.Päivi Marjamäki. Imaging of dopamine and serotonin transporters Pre-Clinical Studies with Radiotracers for Positron Emission Tomography // Turun Yliopisto University of Turku, 2011. P. 14–15.Cannon Walter B. Bodily changes in pain, hunger, fear, and rage. Appleton-Century-Crofts, 1920. P. 184–214.Cannon Walter B. Bodily changes in pain, hunger, fear, and rage. Appleton-Century-Crofts, 1920. P. 184–214.Keith T., Bolshakov V. Emotional enhancement of memory: how norepinephrine enables synaptic plasticity // Massachusetts: Molecular Brain, 2010. P. 1–3.Keith T., Bolshakov V. Emotional enhancement of memory: how norepinephrine enables synaptic plasticity // Massachusetts: Molecular Brain, 2010. P. 1–3.Gregory A.O., Michael A.S., Frazer A. Brain Norepinephrine: Neurobiology and Therapeutics. New York: Cambridge University Press, 2007. P. 157–257.Gregory A.O., Michael A.S., Frazer A. Brain Norepinephrine: Neurobiology and Therapeutics. New York: Cambridge University Press, 2007. P. 157–257.Gewaltig Marc-Oliver, Diesmann Markus. NEST (NEural Simulation Tool) // Scholarpedia. 2007. V. 2, No 4. P. 1430. URL: http://www.scholarpedia.org/article/ NEST_(NEural_Simulation_Tool).Gewaltig Marc-Oliver, Diesmann Markus. NEST (NEural Simulation Tool) // Scholarpedia. 2007. V. 2, No 4. P. 1430. URL: http://www.scholarpedia.org/article/ NEST_(NEural_Simulation_Tool).Zaborszkyy L., Anthony van den Pol, Gyengesi E. The Basal Forebrain Cholinergic Projection System in Mice. Academic Press Elsevier, 2012. 686 p.Zaborszkyy L., Anthony van den Pol, Gyengesi E. The Basal Forebrain Cholinergic Projection System in Mice. Academic Press Elsevier, 2012. 686 p.Mcdonlad A.J., Mascagni F. Colocalization of calcium-bindinf propertis and GABA in neurons of the rat basolateral amygdala // Department of Cell Biology and Neuroscience, 2000. P. 681–693.Mcdonlad A.J., Mascagni F. Colocalization of calcium-bindinf propertis and GABA in neurons of the rat basolateral amygdala // Department of Cell Biology and Neuroscience, 2000. P. 681–693.Masuko S., Nakajima Y., Nakajima S., Yamaguchi K. Noradrenergic neurons from the Locus Ceruleus in dissociated cell culture: culture methods, morphology, and electrophysiology // Journal of Neuroscience. 1986. P. 3229–3241.Masuko S., Nakajima Y., Nakajima S., Yamaguchi K. Noradrenergic neurons from the Locus Ceruleus in dissociated cell culture: culture methods, morphology, and electrophysiology // Journal of Neuroscience. 1986. P. 3229–3241.Gary Aston-Jones, Yan Zhu, J. Patrick. Card numerous GABAergic afferents to Locus Ceruleus in the pericerulear dendritic zone: possible interneuronal pool // Journal of Neuroscience. 2004. P. 2313–2321.Gary Aston-Jones, Yan Zhu, J. Patrick. Card numerous GABAergic afferents to Locus Ceruleus in the pericerulear dendritic zone: possible interneuronal pool // Journal of Neuroscience. 2004. P. 2313–2321.Hui-Ling Wang, Marisela Morales. Pedunculopontine and laterodorsal tegmental nuclei contain distinct populations of cholinergic, glutamatergic and GABAergic neurons in the rat // Eur. J. of Neuroscience. 2009. P. 340–358.Hui-Ling Wang, Marisela Morales. Pedunculopontine and laterodorsal tegmental nuclei contain distinct populations of cholinergic, glutamatergic and GABAergic neurons in the rat // Eur. J. of Neuroscience. 2009. P. 340–358.Gavrilovici C., D’Alfonso S., O. Poulter M. Diverse interneuron populations have highly specific interconnectivity in the rat piriform cortex // Journal of Comparative Neurology. 2010. P. 1570–1588.Gavrilovici C., D’Alfonso S., O. Poulter M. Diverse interneuron populations have highly specific interconnectivity in the rat piriform cortex // Journal of Comparative Neurology. 2010. P. 1570–1588.Rockhold R.W., Liu N., Coleman D., Commiskey S., Shook J., Ho I.K. The nucleus paragigantocellularis and opioid withdrawal-like behavior // Journal of Comparative Neurology. 2010. P. 270–276.Rockhold R.W., Liu N., Coleman D., Commiskey S., Shook J., Ho I.K. The nucleus paragigantocellularis and opioid withdrawal-like behavior // Journal of Comparative Neurology. 2010. P. 270–276.Ford B., Colin J., Holmes Mainville L., Barbara E. GABAergic neurons in the rat pontomesencephalic tegmentum: codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus // Journal of Comparative Neurology. 1995. P. 177–196.Ford B., Colin J., Holmes Mainville L., Barbara E. GABAergic neurons in the rat pontomesencephalic tegmentum: codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus // Journal of Comparative Neurology. 1995. P. 177–196.Akira Monji, Nobumitsu Morimoto, Iwao Okuyama, Kazuo Umeno, Ikuko Nagatsu, Yasuhiko Ibata, Nobutada Tashiro. The number of noradrenergic and adrenergic neurons in the brain stem does not change with age in male Sprague-Dawley rats // Brain Researh. 1994. P. 171–175.Akira Monji, Nobumitsu Morimoto, Iwao Okuyama, Kazuo Umeno, Ikuko Nagatsu, Yasuhiko Ibata, Nobutada Tashiro. The number of noradrenergic and adrenergic neurons in the brain stem does not change with age in male Sprague-Dawley rats // Brain Researh. 1994. P. 171–175.

The authors declare that there are no conflicts of interest present.